Question

65.Sources of ATP in nervous system. Role of glucose and ketone bodies.

(please more explanation Im medicine student) Thank you...

Answer 1

As ATPis ubiquitous in nature all metabolically active cell produce ATP by the same process of including neurons the ATP if formed from ADP by oxidative phosphorylation this process occurs majorly other process are lactic acid fermentation , and sometimes stored ATP is used for the body to use .

The glucose acts as the main source of energy as its oxidative phosphorylation gives ruse to formation of ATP glucose is used by the whole body for the formation of ATP hence it is an important food to keep the life working but in cases of starvation fatty acids are metabolised which give rise to ketone bodies. These are not bad for us these are good but we study that due to ketone bodies ketoacidosis occur , kidney damage occurs all of this is due to over production of ketone bodies at a normal amount it helps in compensating the ATP production without glucose by changing itself to acetyl coA which then goes into creb cycle for the production of ATP . These process occur all over the body but in brain the kheton bodies are also transformed into long chain fatty acids which are triglycerides phospholipid and cholesterol. There are used for as source of energy in brain .this process only occur in brain .