Question

40.Supporting metabolic role of liver under physical exercise.

-biochemistry

(please more explanation Im medicine student)

Answer 1

Prolonged acute exercise reduces hepatic blood flow, stimulating hepatic glycogenolysis, gluconeogenesis and synthesis of some proteins; however, lipid metabolism shows little change.

Liver adapts to repeated demands of exercise by increasing its capacity to produce energy by oxidizing fat. So regular exercise can reduce hepatic fat.

The ability of regular physical activity to increase fat oxidation is protective and can reverse fatty liver disease and therefore enhance liver health

Regular aerobic exercise training improves blood glucose control during exercise by increasing glycogen stores and up-regulating enzymes involved in gluconeogenesis and carbohydrate metabolism.

Resistance to oxidant stress is generally increased by training. Lipogenic enzymes are down-regulated, and lipid metabolism is augmented.

Also, modulations of insulin, insulin-like growth factor, glucagon and interleukin-6 may trigger the adaptive responses to training.