Which of the following types of T-cells would be considered the “youngest” type and the "oldest"...

Which of the following types of T-cells would be considered the “youngest” type and the "oldest" type?

a. Effector T-cell

b. Immature T-cell

c. Naive T-cell

Solutions

Expert Solution

Youngest - Immature T cells
Oldest - Effector T cells
Explanation: Immature T cells ( T stem cells ) are formed from hematopoetic stem cells . Immature T cells migrate to thymus gland where they differentiate , proliferate and mature to T cells and thus, become active after becoming mature . It is not ready to encounter pathogen.
NAive T cells - It is also considered immature unlike activated T cells . It can however respond to pathogen , and it results in initiation of immune response. Naive T cells can interact with antigen presenting cells that uses an MHC molecule to present antigen .
Effector cells - Naive T cells mature and proliferate into into effector T cells , It interacts with host cell not with the pathogen to carry out immune response. They use coreceptors like CD8 or CD 4. Naive T cells with CD8 become effector cytotoxic T cells and those with CD4 becomes effector T helper cells .

gladiator answered 1 year ago

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