Question

Which of the following are antigen-presenting cells?

• Macrophages

• B cells

• Cytotoxic T cells

• All of these choices are correct answers.

• Only the first and second choices are correct answers.

Answer 1

Only the first and second answer that is Macrophages and B cells are antigen presenting cells along with dendritic cells(not in the option).

The cells which has major histocompatibility complex (MHC) on their cell surface are called antigen presenting cells. T cells recognise these MHCs and perform the antigen reaction.

Antigen presenting cells are essential for adaptive immune responses. The functioning of cytotoxic T cells and Helper T cells are depended on Antigen presenting cells.

Example: if any virus enters into the body the macrophages, B cells or dendritic cells try to ingest the virus and activate the adaptive immune response by creating specific antibody with the help of MHC.

• Macrophages have the capability to invade HIV with CD4+ receptor interractii.
• B cells secret specific antibody which binds with specific B cell receptor (BCR) and perform adaptive immune response.

There are some non professional antigen presenting cells which are:

1. Glial cells
2. Fibroblasts
3. Thymic epithelial cells
4. Thyroid epithelial cells
5. Vascular ensdendothe cells