1. Which of the following would be considered stromal cells (Choose all that apply): a. Macrophages...

1. Which of the following would be considered stromal cells (Choose all that apply):

a. Macrophages in adipose tissue

b. Microglia in brain tissue

c. Beta cells in the pancreas

d. Connective tissue cells surrounding muscle tissue

2. Is cell growth/proliferation promoted or inhibited when these events occur:

AMPK is inactivated: Inhibit or Promote

Rheb is in its GTP-bund state: Inhibit or Promote

Akt phosphorylates in the TSC complex: Inhibit or Promote

P53 drives the expressin f p21: Inhibit or Promote

pRB gets phosphorylated: Inhibit or Promote

Adenylate kinase generate AMP: Inhibit or Promote

Enhanced insulin/IGF1 signaling: Inhibit or Promote

Telemorase attrition: Inhibit or Promote

Solutions

Expert Solution

Hi Answer:

Q. 1. Which of the following would be considered stromal cells (Choose all that apply):

Answer: Option A & D [Macrophages in adipose tissue and Connective tissue cells surrounding muscle tissue]

The stromal cells are the connective tissue cells of any organ. These cells support the function of parenchymal cells of that organ. In addition to this stromal cells play an active role in inflammation responses and also controlling the amount of cells accumulating at an inflamed region of tissue.

Q. 2. Is cell growth/proliferation promoted or inhibited when these events occur:

Answer:

AMPK is inactivated: Promotes the cell growth/proliferation

Rheb is in its GTP-bund state: Promotes the cell growth/proliferation

Akt phosphorylates in the TSC complex: Inhibit the cell growth/proliferation

P53 drives the expression of p21: Inhibit the cell growth/proliferation

pRB gets phosphorylated: Promotes the cell growth/proliferation

Adenylate kinase generate AMP: Promotes the cell growth/proliferation

Enhanced insulin/IGF1 signalling: Promotes the cell growth/proliferation Telomerase attrition: Inhibit the cell growth/proliferation

gladiator answered 1 year ago

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