Explain why broad spectrum antibiotics can exacerbate the infection.

Expert Solution

Answer- Broad spectrum antibiotics as the name suggests it applies for wide range of disease causing by Bacteria. It is used when bacterial is being suspected but the group of its still unknown.

So, Broad spectrum antibiotics exacerbate the infection because as we know trillions of bacteria resides or colonize into the human body. Due to broad nature it disrupting the normal microbiome. Due to disruption of normal bacterial flora leads to disrupt immunity, nutrition, and relative overgrowth is being seen.

And so any overgrowth against the drug leads to secondary infections.This leads infection to last for long and taking cost more to treat also .

Example of broad spectrum antibiotics are tetracycline.

Mechanisms that are developed to resistance against the antibiotics-

1. Decrease permeability of the drug

2. increase drug efflux

3. Decrease affinity of the drug by ribosome binding sites.

4. Enzymatic inactivation of the drugs.

Nightingale answered 3 years ago

One of the attending Physicians in your clinic is known for prescribing broad-spectrum antibiotics for patients....

One of the attending Physicians in your clinic is known for prescribing broad-spectrum antibiotics for patients. What is wrong with this approach and what would be a better way to prescribe antibiotics.

Following a 14-day course of broad-spectrum antibiotics for the treatment of sepsis, a client develops watery...

Following a 14-day course of broad-spectrum antibiotics for the treatment of sepsis, a client develops watery diarrhea attributed to the elimination of normal intestinal flora. What other phenomena are most likely accompanying the low levels of normal flora? A. Decreased mineral and nutrient absorption; decreased carbohydrate metabolism B. Decreased pH of the stomach; increased pH of the lower gastrointestinal tract C. Decreased fermentation of undigestible dietary residue; decreased vitamin absorption D. Proliferation of vitamin K; lower gastrointestinal bleeding Which scenario...

Why is it preferable, if possible, to take a narrow spectrum antibiotic over a broad spectrum...

Why is it preferable, if possible, to take a narrow spectrum antibiotic over a broad spectrum antibiotic? Group of answer choices narrow spectrum antibiotics have a limited range of effectiveness among different bacterial species but they each have several modes of action which make them more effective than broad spectrum antibiotics narrow spectrum antibiotics are less likely to be overcome by antimicrobial resistance mechanisms compared to broad spectrum antibiotics narrow spectrum antibiotics always have a high theraputic index compared to...

7. Distinguish between broad-spectrum and narrow-spectrum antimicrobials?

A number of antibiotics inhibit the function of ribosomes. Why can some of these antibiotics cause...

A number of antibiotics inhibit the function of ribosomes. Why can some of these antibiotics cause side effects in which mitochondrial function is impaired

1. Antibiotics are more effective when the bacteria causing an infection are actively growing. Why do...

1. Antibiotics are more effective when the bacteria causing an infection are actively growing. Why do you think this is? During which phase of growth( lag,log,stationary,or death) do you think antibiotics are most effective?

Antimicrobial Drugs 1. Why do antibiotics that target bacterial protein synthesis usually have a broader spectrum...

Antimicrobial Drugs 1. Why do antibiotics that target bacterial protein synthesis usually have a broader spectrum of activity compared to antibiotics that target the peptidoglycan integrity? 2. If your only treatment option is a highly toxic antibiotic (such as chloramphenicol), how could you adjust the treatment protocol to lessen its negative effects? 3. Suppose that a patient that suffers from a Gram-positive bacterial infection develops an allergic reaction to amoxicillin. What alternative antimicrobial treatment from the same general group of...

Question

Explain why broad spectrum antibiotics can exacerbate the infection.

Solutions

Expert Solution

Related Solutions