In: Nursing
medication trade or generic name
dose and route per drug book (drug frequency and administration instruction)
drug classification
indications/uses
Action/effect (what is expected patient response to MOA
main side affect/adverse reaction (any significant, medical alerts, warnings/percutions, drug interactions, contraindications
Nursing intervention ( assessment-BP, AP, resp, I7O, weight, finger stick) and lab values to be moniyored pre/post med. admin & patient teaching) of the following:
Ondansetron
Acetaminophen
docusate sodium
folic acid
Lorazepam
APA reference
Ondansetron | Acetaminophen | docusate sodium | Folic acid | Lorazepam | |
Generic Name | Zofran, Zophren |
Paracetamol Acatol, calpol, tylenol,Anacin,Dolanex |
dulcolax stool softner |
Folate sodium. folacin, Folvite Novofolacid |
Ativan |
Dose and Route | Injection 2mg/mL IV/IM. Tab. 24mg/day is recommended. available in 8mg. |
Tablets: 80mg,120mg,325mg,500mg. Suppositories: 80mg,120mg,125mg,300mg,325mg,650mg. Injections: 80mg/0.8mL, 80mg/0.25mL,120mg/5mL, 160mg/5mL,500mg/5mL IM/IV |
Tablet: 100mg Capsules: 50mg,100mg,240mg,250mg. Syrup: 50mg/15mL,60mg/15mL,150mg/15mL |
Tablet: 0.4mg,0.8mg,1mg. Injection: 5mg/mL. |
Tablets: 0.5mg,1mg,2mg Oral solution: 2mg/mL Injection: 2mg/mL. |
Drug classification | Antiemetic | NonNarcotic Analgesic, Antipyrectic | Laxatives | Vitamin B9 | Anxiolytic, sedative-hypnotic. |
Indication/uses | Prevention of nausea and vomiting | Fever, minor aches, pains | Constipation, avoid straining during defecation. | folate deficiency, macrocytic anemia, megaloblastic anemia, inadequate dietary intake, pregnancy. | anxiety disorders, status epileptics. |
Side effects | Headache, constipation, painful urination, fatigue. | Nausea, itching, rashes, headache, clay-colored stool. | abdominal cramps, diarrhea, nausea, rash. | Nausea, fatigue, trouble sleeping, weight loss, muscular pains, mental depression. |
Increased sleeping, confusion, hallucinations, muscle weakness, trouble in swallowing. |
General alerts | Avoid in patients hypersensitivity to ondansetron and liver disease patient. | Hypertoxicity, acute poisoning, and chronic ingestion lead to neutropenia, leukopenia. | hepertoxicity. | CNS depression, Gi disorders, Sensory impairment. | |
Warnings/precautions | Not recommended for pregnant, breastfeeding woman and children under 4 years. | Cholestyramine may decrease the acetaminophen absorption. | warnings with congestive heart failure, DM, edema. | use with caution during lactation. | Renal, hepatic impairment, myasthenia gravis, narrow-angle glaucoma, GI disorders |
Drug Interaction | Interaction with alcohol and medicines like Amitriptyline, carbamazepine, Amiodarone, apomorphine. |
Interact with alcohol. Interact with drugs such as carbamazepine, phenytoin, rifampicin. |
Interact with mineral oil. | Interact with chloramphenicol, phenytoin |
Interact with alcohol, cimetidine. Interact with clozapine, sodium oxybate. |
Contraindications | Ecg changes, pregnancy, breastfeeding, hepatic impairment. | Hypersensitivity, allergies. | Atonic constipation, sodium restricted patient, fecal impaction, intestinal obstruction, colon, structural anomalies of the colon. | pernicious anemia, aplastic anemia, undiagnosed anemia | Pregnancy, lactation, narrow-angle glaucoma, alcohol intoxication. |
Nursing intervention |
Monitor fluid and electrolyte status. check vital signs. Monitor cardiovascular status. |
Check vital signs. Assess for signs and symptoms. Check for hepatotoxicity. |
Use periodically with the interval of 3 days. Check for diarrhea. |
Obtain a detailed history of drug intake, alcohol usage, oral contraceptives, barbiturates. Assess for fatigue, weakness, dyspnea. Monitor patient's therapeutic plasma levels. |
Check for signs and symptoms. Check CBC count and liver function periodically in long-term therapy. Check for mood disorders or changes. |
Patient teaching | Aware of side effects and allergies to Ondansetron. |
Do not self-medicate without doctor prescription. Educate about the drug overdose and side effects. |
Encourage more amounts of fluids. Avoid use of mineral oil. Do not take for prolonged periods of time. |
Educate about the diet rich in folic acid. Inform that the urine in yellowish color. Look for rash or any side effects. |
Educate about the side effects. Give warnings about sleepiness during the daytime. Do not withdraw from the medication suddenly. |