Question

What role does the destruction of neurotransmitters play in the functioning of neurons and muscle cells?

Answer 1

Neurotransmitters act as chemical messengers which transmits signals across a chemical synapse such as from one neuron to another or in the neuromuscular junction. They are relaesed in synaptic vesicles in synaptic clefts where they are picked up by the receptors on the target cell. Major neurotransmitters include acetylcholine to amino acids to peptides, monoamine, purines.

Destruction of the neurotransmitter would result in the inhibition of the transmission of signals; no generation of excitatory signals or action potentials subsequently thus leading to tremors, inability to move, shaking. Dopamine when not transmitted would eventually result in Parkinson's disease. Other diseases include Attention Deficit Hyperactivity Disorder, autism, depression etc.

. Acetylcholine is the main neurotransmitter in neuromuscular junction involved in stimulation of muscle.In muscle cells, it would result in stiffness, muscular cramps, pain, shaking and even paralysis if the neurotransmitter of the muscle cells is destroyed