Question

Dietary fat refers to triglycerides. Triglycerides are hydrolyzed into __glycerol__________ and __3 fatty acids___________.

1. Explain how each of these hydrolysis products are used to create energy for the body.

2. Which tissues benefit from each hydrolysis product?

Answer 1

Answere :

Question 1 :

Triglycerides are broken down into two principle component i.e. Fatty acid and glycerol. Fatty acids are oxidized by Beta-oxidation into Acetyl-CoA, which is used by kreb cycle. The glycerol that is released directly enter into glycolysis through Dihydroxyacetone Phosphate (DHAP).

Beta-oxidation begins in the cytoplasm, fatty acids are converted into fatty acyl coA molecules. Fatty acyl CoA combine with carnitine to create acyl carnitine molecule, which help to transport fatty acid across mitochondrial membrane. Once into mitochondrial membrane, acyl carnitine molecule fatty acyl Co-A and then to acetyl-CoA l. This acetyl CoA enters into kreb cycle and is used to produce ATP in the same way as acetyl CoA derived from pyruvate.

The glycerol is converted into glycerol-3-phophate then converted to DHAP. This DHAP is converted into glyceraldehyde 3-phosphate (or GAP). This GAP is then enter into glycolysis.

Question 2 : The fats is stored in adipose tissue and liver. The hydrolysis of fats result in no excessive storage of fats in liver. So, accurate balance occur between fat breakdown and synthesis.