In: Biology
Explain how the ATP generated by ATP synthase in the mitochondrion can be used in other parts of the cell?
Answer
ATP synthesis occurs in the mitochondria during the oxidation of glucose. Oxidation of glucose occurs in three steps first is glycolysis second one is kreb cycle than last on is oxidative phosphorylation. In which glycolysis occurs in cytoplasm produces ATP (substrate level phosphorylation) and NADH. kreb cycle occurs in mitochondria produces NADH and Co2 and next step of glucose oxidation is oxidative phosphorylation in which all the NADH are oxidaize produces election. election move through the many electron acceptors present in inner membrane of mitochondria. During the movement of electron protons are transported through the complete First , third and fourth again the concentration from to matrix to IMS . Than again proton come back along the concentration from ims to matrix through the F1 particles or ATP synthase. One ATP synthesis required 4 Protons in which three move through the ATP synthase and one required for the phosphate and proton symportor.
1NADH = 10 proton/4 =2.5 ATP
1FADH =6/4 = 1.5 ATP