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Compare and contrast the four types of diuretics for uses, side effects, precautions, and contraindications. Please...

Compare and contrast the four types of diuretics for uses, side effects, precautions, and contraindications. Please make sure you cite your references used in APA format. Thank you

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Expert Solution

Diuretics

A diuretic is any substance that promotes diuresis, the increased production of urine.

4 types of diuretics with use, sideeffects,precaution, contraindications

Diuretic Use sideeffects Precautions Contra indications
Thiazide diuretics

• Hypertension

• Chronic, mild- heart failure

• Edema

• Nephrogenic Diabetes insipidus

• Prevention of Ca++ excretion in osteoporosis and calcium nephrolithiasis

  • dizziness
  • lightheadedness,
  • blurred vision,
  • loss of appetite,
  • itching,
  • stomach upset,
  • headache, and
  • weakness.
  • renalelectrolyte disturbances
  • gout,
  • hyperglycemia,
  • hypotension
  • Hypotension.
  • Allergy to sulfa drugs.
  • Gout.
  • Hypokalemia.
  • Renal failure.
  • Lithium treatment
Loop diuretics

• Congestive heart failure

• Acute pulmonary edema

• Edema due to renal failure, nephrotic syndrome, ascites

• Hypercalcemia (that induced by malignancy)

• Severe hypertension

• Force diuresis during drug/chemical intoxication

  • hyponatremia
  • hypokalemia,
  • hypomagnesemia
  • dehydration,
  • hyperuricemia
  • gout
  • dizziness,
  • postural hypotension,
  • syncope.
  • Have severe liver or kidney disease
  • Dehydration
  • Have an irregular heartbeat
  • pregnancy and/or have developed high blood pressure during your pregnancy
  • age 65 or older
  • gout
  • allergic to sulfa drugs, like Septra and Bactrim (sulfamethoxazole with trimethoprim)
  • Anuria.
  • Hypersensitivity to furosemide, bumetanide or torsemide
  • Hepatic coma.
  • Severe electrolyte depletion.
oOsmotic diuretics
  • Removal of nephrotoxic substances
  • lower intracranial pressure and for short-term reduction of intraocular pressure.
  • Extracellular volume expansion
  • heart failure
  • pulmonary edema.
  • Headache
  • Nausea and vomiting
  • Dehydration and loss of free water
  • Hypernatremia or increased sodium levels

Renal or hepatic disease. pregnancy

lactation

  • Hepatic disease or insufficiency.
  • Long-term use in glaucoma.
  • Hyponatremia, hypokalemia.
  • Hyperchloremic metabolic acidosis.
  • Adrenocortical insufficiency.
  • Severe renal insufficiency.

Potassium-sparing diuretics

heart failure

Prevent pottasium loss

Increase the amount of fluid passed from the body in urine

  • Hyperkalemia
  • Hyperchloremic metabolic acidosis
  • Gynecomastia or breast enlargement in males
  • Erectile dysfunction
  • Benign prostatic hyperplasia
  • Acute renal failure
  • Kidney stones

Pregancy

Lactation

Hepatic or renal disorders

  • Hyponatremia
  • Hypoklaemia
  • Adrenocortical insufficiency.
  • Severe renal insufficiency.
  • Hepatic disease or insufficiency.
  • Long-term use in glaucoma.

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