In the first and second trimester of pregnancy the uterus is relatively unresponsive to oxytocin but during the last weeks of pregnancy becomes increasingly responsive (meaning it will cause contractions). With your understanding of how cells respond to hormones, explain why this is the case. You must include in general how the cells change as well as the specific hormone(s) that trigger the change.

Using bullet-point sentences, describe EVERY SINGLE action from the action potential moving down a motor neuron, to the synapse, and then all the way to contraction of the skeletal muscle cell.

16 years old male patient who has had bleeding gums & skin rash over last few days, he asked medical advice & here are his laboratory results: HB: 12 g/dl WBCs: 6000 PLT: 40000 Bleeding time: 12 min INR:1.1 PTT: 35 second Which of the following is the most probable diagnosis: Select one: a. Idiopathic Thrombocytopenic Purpra (ITP) b. None of the above c. Hemophilia A d. Von Willebrand disease

why partial agonist is unable to reach the maximal response?

A toxin found in shellfish blocks voltage-gated Na+ channels from opening in somatic motor neurons. What effect would this have on nerve and muscle function?

Neurons wouldn’t depolarize; muscle would contract continuously (spastic paralysis)

Neurons wouldn’t repolarize; muscle would be unable to contract (flaccid paralysis)

Neurons wouldn’t repolarize; muscle would contract continuously (spastic paralysis)

Neurons wouldn’t depolarize; muscle would be unable to contract (flaccid paralysis)

Neurons wouldn’t depolarize, but this would not affect muscle function

Choose a therapeutic device and write a report stating the following:

1. Definition

2. Physical principles of operation and functions

(how the device behaves at different conditions of the patient)

3. Examples

4. References

Summarise the timecourse of the IL-6 response to an acute bout of prolonged strenuous exercise, and evaluate the major source of IL-6 secreted in response to exercise and the purpose of its secretion. (200 words)

1. Regarding normal aging, which of these statements is FALSE?
   1. Amyloid plaques can be seen in the brain of healthy seniors (normal aging).
   2. Ageism is a form of age discrimination that can affect both the elderly and the young.
   3. Compared to young people, the brain of the elderly person generally needs less neural resources to accomplish a similar task.
   4. The brain volume decreases by about 2% per decade during adulthood to older age.
   5. Anatomical changes in the brain during aging are different depending on the brain region.

Describe the three classical components of the open-window hypothesis, and evaluate whether each of these components supports the theory that prolonged strenuous exercise suppresses the immune system. (200 words)

Certain forms of exercise can lead to soreness arising from muscle damage. Discuss the aetiology of this soreness and evaluate its implications for exercise performance. (200 words)

What anatomical feature limits maximal ventilation

7. Identifying Body Planes: Complete the following chart as you ID the anatomical planes of section represented by the anatomical models in the classroom.