Sexually reproducing organisms use a variety of strategies to compensate for the gene dosage differences arising...

Sexually reproducing organisms use a variety of strategies to compensate for the gene dosage differences arising from different numbers of X-chromosomes present in males and females. Please describe how dosage compensation of X-chromosome is achieved in mice and Drosophila (fruit flies)?

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Expert Solution

In case of Drosophila male has only one X chromosome and female has two chromosome. In this case male two fold the transcription of X chromosome in male to compensate with female.

while mouse has same sex chromosome compared to humans . so there is inactivation of one X chromosome in female for dosage compensation of X chromosome.

gladiator answered 2 years ago

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