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In: Chemistry

Taken Organic Chemistry Second Edition! We are in the third week, and I need a conclusion...

Taken Organic Chemistry Second Edition! We are in the third week, and I need a conclusion of of the report.

We are testing Aspirin Products

we used buffered aspirin, 10% of NaOH, 1% FeCl3

Can I get a conclusion of the report. Need this as soon as possible.

Solutions

Expert Solution

Aspirin is the drug most widely used in modern society. The name derives from its structure aspirin, acetylsalicylic acid. Formerly the salicylic acid was known as spiraerico acid (Spiraea ulmaria of) and therefore aspirin was acetilespiraerico acid, which derived its name.
Aspirin is, even today, one of the drugs most widely used and known worldwide consumption for its analgesic, antipyretic and anti-inflammatory effect on the body. Aspirin inhibits prostaglandin biosynthesis, compounds that induce pain, inflammation and fever. Also it poses a moderate aspirin derivative anticoagulant effect exerted in inhibiting thromboxane biosynthesis, a platelet aggregator, and that has led to their use in the prevention of myocardial infarction and of heart attacks by thrombus formation.
Salicylic acid itself is an analgesic. This is the product that is extracted from various plants and is able to relieve pain. Initially, the drug is administered as the sodium salt. However, the use of sodium salicylate was producing troublesome side effects and drug modification would retain the therapeutic properties without exhibiting undesirable side effects was sought. By treatment with acetic anhydride salicylic acid, acetylsalicylic acid, as effective as sodium salicylate compound is obtained, but of reduced side effects. This same strategy was used later for the modification of a powerful painkiller, morphine.

In this case the problem was its ability to create addiction and, with the idea to solve it, acetylated morphine, heroin obtained, there is no doubt that in this case the strategy was not as successful as in salicylic acid.
The starting material for the manufacture of aspirin is salicylic acid which, in turn, is prepared as the sodium salt sodium phenoxide by treatment with carbon dioxide to about 5 atm and a temperature of 125


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