In: Chemistry
Taken Organic Chemistry Second Edition! We are in the third week, and I need a conclusion of of the report.
We are testing Aspirin Products
we used buffered aspirin, 10% of NaOH, 1% FeCl3
Can I get a conclusion of the report. Need this as soon as possible.
Aspirin is the drug most widely used in modern society. The name
derives from its structure aspirin, acetylsalicylic acid. Formerly
the salicylic acid was known as spiraerico acid (Spiraea ulmaria
of) and therefore aspirin was acetilespiraerico acid, which derived
its name.
Aspirin is, even today, one of the drugs most widely used and known
worldwide consumption for its analgesic, antipyretic and
anti-inflammatory effect on the body. Aspirin inhibits
prostaglandin biosynthesis, compounds that induce pain,
inflammation and fever. Also it poses a moderate aspirin derivative
anticoagulant effect exerted in inhibiting thromboxane
biosynthesis, a platelet aggregator, and that has led to their use
in the prevention of myocardial infarction and of heart attacks by
thrombus formation.
Salicylic acid itself is an analgesic. This is the product that is
extracted from various plants and is able to relieve pain.
Initially, the drug is administered as the sodium salt. However,
the use of sodium salicylate was producing troublesome side effects
and drug modification would retain the therapeutic properties
without exhibiting undesirable side effects was sought. By
treatment with acetic anhydride salicylic acid, acetylsalicylic
acid, as effective as sodium salicylate compound is obtained, but
of reduced side effects. This same strategy was used later for the
modification of a powerful painkiller, morphine.
In this case the problem was its ability to create addiction
and, with the idea to solve it, acetylated morphine, heroin
obtained, there is no doubt that in this case the strategy was not
as successful as in salicylic acid.
The starting material for the manufacture of aspirin is salicylic
acid which, in turn, is prepared as the sodium salt sodium
phenoxide by treatment with carbon dioxide to about 5 atm and a
temperature of 125