through a mechanistic analysis of the electrophilic aromatic
substitution of acetamidobenzene, explain why this compound mainly
substitutes mainly para. Suggest a reason why the reaction rate of
acetamidobenzene with electophiles is slower than the rate of the
reaction of aniline with electrophiles.
What is the difference between:
acid-base
oxidation-reduction
nucleophilic substitution
elimination
electrophilic addition
nucleophilic addition
electrophilic aromatic substitution
If you can provide an example, that would be great :)
Why
is electrophilic aromatic substitution (preparation of methyl
m-nitrobenzoate important in the real world? Why is it useful and
why do people care about it? Please specifically state its
significance and how it benefits society. What should one learn
from performing this reaction?
Organic II lab: Relative Rates of Electrophilic Aromatic
Substitution
In this experiment, acetic acid is used as a catalyst for the
electrophilic substitution on aromatic rings. Would this catalyst
work with nitrobenzene? Explain your answer.
_______________________________________________
I performed an electrophilic aromatic substitution- iodination
of salicylamide.
I used 1.012 g of solid salicylamide in 20 mL ethanol. 1.205 g
of sodium iodide was also added. Then I placed the solution in an
ice bath for 5 min and after this time 7.0 mL of 8.25% NaOCl was
added.
What is the expected product and why?
(At the end of lab, and IR was obtained and this indicated the
product to be a 1,2,4-trisubstituted aromatic compound).
What is...
QUESTIONS FOR m-Dinitrobenzene lab (Nitration of the aromatic
molecules)
1) what effect would the use of concentrated nitric acid in
place of the fuming nitric acid have on the yield on
m-dinitrobenzene? Explain Fully.
2) During the washing of the "crude" Product, the filtrate was
checked with pH paper as it dripped from the funnel. Why was this
done rather then check the filtrate that collected in the suction
flask? Explain Fully.
3) give the name and formula of the...
1. Why iodoethane is preferred in Williamson et her synthesis
over chloroethane ?
2. Write the balanced equation for reaction of acetaminophen
with K 2 CO 3 .
3. You will wash your reaction mixture at the end of reaction
with water and then with 5% aqueous NaOH. What you will remove from
the reaction mixture by w ashing with (a) water, (b) aqueous
NaOH