Explain why the methoxy group is a good activator and ortho-
para director in electrophilic aromatic substitution reactions. Use
resonance forms and the Wheland intermediate in your answer.
1. synthesis scheme of Electrophilic Aromatic substitution:
Nitration of Fluorene Synthesis of 2,4,5,7-Tetranitrofluorene
2. write a detail mechanism for the formation of
tetranitrofluorene from Fluorene.
Why
is electrophilic aromatic substitution (preparation of methyl
m-nitrobenzoate important in the real world? Why is it useful and
why do people care about it? Please specifically state its
significance and how it benefits society. What should one learn
from performing this reaction?
through a mechanistic analysis of the electrophilic aromatic
substitution of acetamidobenzene, explain why this compound mainly
substitutes mainly para. Suggest a reason why the reaction rate of
acetamidobenzene with electophiles is slower than the rate of the
reaction of aniline with electrophiles.
which of the following substituents will direct the
incoming group to the ortho/para position during electrophilic
aromatic substitution
a) -NO2
b) -CF3
c)-Br
d) -COOCH3
e) -COCH3
What is the difference between:
acid-base
oxidation-reduction
nucleophilic substitution
elimination
electrophilic addition
nucleophilic addition
electrophilic aromatic substitution
If you can provide an example, that would be great :)
Organic II lab: Relative Rates of Electrophilic Aromatic
Substitution
In this experiment, acetic acid is used as a catalyst for the
electrophilic substitution on aromatic rings. Would this catalyst
work with nitrobenzene? Explain your answer.
_______________________________________________
I performed an electrophilic aromatic substitution- iodination
of salicylamide.
I used 1.012 g of solid salicylamide in 20 mL ethanol. 1.205 g
of sodium iodide was also added. Then I placed the solution in an
ice bath for 5 min and after this time 7.0 mL of 8.25% NaOCl was
added.
What is the expected product and why?
(At the end of lab, and IR was obtained and this indicated the
product to be a 1,2,4-trisubstituted aromatic compound).
What is...