Question

In: Biology

You are studying how changes in blood pH might be controlled by homeostasis. In a trial,...

You are studying how changes in blood pH might be controlled by homeostasis. In a trial, you let a mouse run on a treadmill for a fixed period of time, and then you measure its blood pH. Intriguingly, you observe the blood pH drops (more acidic) as carbon dioxide is released into the bloodstream. Which component of the homeostatic feedback system is responsible for producing the correct response if the blood pH is far enough from normal that a response is necessary?

Solutions

Expert Solution

The blood pH should always be maintained in a narrow range [7.35-7.45] for smoot functioning of the body.

Any sudden cange in the body's pH is corrected by different homeostatic mechanisms. The major role is played by the Kidneys and the Lung.

Here in this experiment, if the blood pH falls more i.e becomes more acidic after an exercise the possible explanation for that is lactic acidosis [i.e accumulation of lactic acid in the exercising muscle due to anaerobic metaboism]

The body has different mechanisms to correct that and the major ones are:

1. Increase in the Respiratory rate. Tis causes more CO2 washout from the lungs. CO2 washout always makes the pH towards the alkaline side. so this can correct our acidosis.

2. Second mechanism is the Renal regulation of pH. Kidneys increase acid excretion (intercalated cells secrete H+ into tubules) and decrease bicarbonate excretion. When intercalated cells secrete H+ into the tubule, it combines with buffers in the lumen (ammonia) and is excreted.


Related Solutions

Describe how vertebrates maintain blood glucose homeostasis. Why is the regulation of blood glucose levels so...
Describe how vertebrates maintain blood glucose homeostasis. Why is the regulation of blood glucose levels so important for the success of vertebrates? Compared with squid and shrimp, vertebrates can tolerate longer periods of anaerobic activity. Explain the metabolic adaptations that make this possible.
How might changes in the net neutrality rules directly impact businesses? How might the proposed changes...
How might changes in the net neutrality rules directly impact businesses? How might the proposed changes indirectly affect businesses through their customer base? How, if at all, should the rules controlling “net neutrality” be modified? Explain fully.
Discuss how calcium homeostasis is maintained in the blood, especially the mechanism of positive regulation of...
Discuss how calcium homeostasis is maintained in the blood, especially the mechanism of positive regulation of calcium levels. What are the two hormones you learned in the class that control the levels of calcium? What classes of hormones are they? List all organs that participate in the processes and their roles. Do you think the administration of calcitonin would help improve the condition of osteoporosis? Briefly defend your argument.
How is the level of cholesterol in the blood stream controlled? Describe and explain how two...
How is the level of cholesterol in the blood stream controlled? Describe and explain how two metabolic defects in humans that could produce an elevated blood cholesterol level. (4 points)
If a patient has a collapsed lung what changes to blood pH are likely to occur?...
If a patient has a collapsed lung what changes to blood pH are likely to occur? Explain why this might happen. How could the body compensate for these changes?
You are studying the genetics of the fruit fly. Body color (brown or black) is controlled...
You are studying the genetics of the fruit fly. Body color (brown or black) is controlled by the b locus and wing size (long or short) is controlled by the vg locus. In cross 1, you mate two true-breeding strains and obtain the following progeny: cross 1: brown, short-winged male X black, long-winged female F1: all brown, long-winged flies a) Which phenotypes are dominant and which phenotypes are recessive? i) The recessive trait for body color is _____________________. ii) The...
Describe how you would design a valid randomized controlled trial to test the hypothesis that Low-Chol,...
Describe how you would design a valid randomized controlled trial to test the hypothesis that Low-Chol, a new oral medication to lower serum cholesterol, decreases the risk of death from coronary heart disease in healthy men, 40-54 years of age, at high risk for the disease. Include in your description how you would select the study sample, determine the subject eligibility criteria, ascertain the appropriate sample size, allocate the subjects into experimental and control groups, apply the intervention, and assess...
change control plan - a brief outline of how changes will be managed/controlled
change control plan - a brief outline of how changes will be managed/controlled
Please describe how you think models of events for the purpose of studying a case might...
Please describe how you think models of events for the purpose of studying a case might influence the outcome and accuracy of the proceeding. Are models and recreations helpful in the pursuit of a just outcome or not
How does exercise affect blood flow to the liver and kidneys? How do changes in blood...
How does exercise affect blood flow to the liver and kidneys? How do changes in blood flow to the liver and kidneys potentially affect drug metabolism and clearance—compare to intensity of exercise? How does blood flow to the muscle change during exercise and what type of drug could this affect? What about stomach blood flow?
ADVERTISEMENT
ADVERTISEMENT
ADVERTISEMENT