Question

List the steps of Glycolysis

Answer 1

GLYCOLYSIS : It is the primary metabolic process of break down of Glucose into simpler compound i.e. Pyruvate  to generate energy ATP. It can occur in both aerobic and anarobic conditon.

1. Hexokinase: converts D-glucose into glucose-6-phosphate. Phosphate group to a molecule derived from ATP.
2. Phosphoglucose Isomerase. - rearrangement of glucose 6-phosphate (G6P) into fructose 6-phosphate (F6P) by glucose phosphate isomerase.
3. Phosphofructokinase : converts fructose 6-phosphate into fructose 1,6-bisphosphate
4. Aldolase splits fructose 1, 6-bisphosphate into two sugars that are isomers of each other.
5. Triosephosphate isomerase.- Inter- converts the mole s dihydroxyacetone phosphate (DHAP) and glyceraldehyde 3-phosphate (GAP).
6. Glyceraldehyde-3-phosphate Dehydrogenase : Adds an inorganic phosphate to glyceraldehyde 3-phosphate, producing 1,3-bisphosphoglycerate.
7. Phosphoglycerate Kinase : transfers a phosphate group from 1,3-bisphosphoglycerate to ADP to form ATP and 3-phosphoglycerate
8. Phosphoglycerate Mutase. relocates the P from 3- phosphoglycerate from the 3rd carbon to the 2nd carbon to form 2-phosphoglycerate.
9. Enolase removes a molecule of water from 2-phosphoglycerate to form phosphoenolpyruvic acid (PEP)
10. Pyruvate Kinase - transfers a P from phosphoenolpyruvate (PEP) to ADP to form pyruvic acid and ATP.