Sperm rely on both microtubules and microfilaments for key biological processes. Explain the role of microtubules...

Sperm rely on both microtubules and microfilaments for key biological processes. Explain the role of microtubules and dynein in movement of sperm. Explain the role of actin in the process of fertilization.

Expert Solution

Microtubule are key component of cilia and flagella present eukaryotic cell such as sperm.
Sperm propel themselves through the motion of flagella containing microtubules.
Microtubules serve as a track for two classes of motor protein namely, kinesins and dyneins.
Dynein drives the motion of one member of each outer pair relative to the other, causing the overall structure to bend.
Tail of the sperm is composed of flagellum , which contain a central skeleton constructed of 11 microtubules collectively termed the axoneme and a thin cell membrane covering the axoneme.
Capacitation of sperm is important in fertilization.
Polymerization of globular (G)-actin to filamentous (F)-actin occurs during capacitation,
(F) -actin formation is important for the transloction of phospholipase C from the cytoplasm to the sperm plasma membrane during capacitation.
(F) -actin should undergo depolymerization prior to acrosome reaction , which enable the fusion of acrosomal membrane and overlying plasma membrane.

Sydney Mullin answered 10 months ago

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