Question

How would the body bring the systems affected by Rheumatoid Arthritis back to homeostasis? (Discuss at least 3 systems afftected by RA and what the systems would do to bring the body back to homeostasis)

Answer 1

The 3 systems affected by RA are immune system ,respiratory system and skeletal system.

Skeletal system,:

RA causes the inflammation in and around the joints. This may damage the skeletal system.the homeostasis of bone is regulated by a coordinated process executed by bone forming and bone resorbing cells. In case of RA the innate and adaptive immune system itself, critically affect bone homeostasis. So the Joint homeostasis is maintained preserving the articular cells to proceed down the differentiation pathway that leads to chondrocyte hypertrophy and bone replacement such as it occurs in the growth plate cartilage.

Respiratory system: The lung problems most often linked to rheumatoid arthritis include: Scarring within the lungs. Scarring related to long-term inflammation (interstitial lung disease) may cause shortness of breath, a chronic dry cough, fatigue, weakness and loss of appetite.

nterstitial lung disease (lung scarring) happens to about 1 in 10 people with RA, according to the Arthritis Foundation.

The scarring refers to damaged lung tissues, which can occur over time from RA-induced inflammation. As inflammation ensues, the body starts attacking lung cells, leading to this type of widespread damage.

Lung scarring may lead to breathing difficulties and related symptoms. These include:

shortness of breath
chronic dry cough
excessive fatigue
weakness
reduced appetite
unintentional weight loss
It’s likely that once you start experiencing symptoms, your lungs already have a significant amount of chronic inflammation.

Immune system:

RA itself is an auto immune disease.Our immune system is an amazing network of cells that protects us from infectious diseases

Rheumatoid arthritis develops when the immune system produces antibodies that attach to the linings of joints. Immune system cells then attack the joints, causing inflammation, swelling, and pain. If untreated, rheumatoid arthritis causes gradually causes permanent joint damage. Treatments for rheumatoid arthritis can include various oral or injectable medications that reduce immune system overactivity