In: Chemistry
what is an enzyme? what is an ES complex?
Enzymes are macromolecular biological catalysts. Enzymes accelerate, or catalyze, chemical reactions.
Basically they are large molecular complexes used to accelerate
biological reactions ONLY by altering the speed of it, they can do
this as follows:
1. Bringing close reacting groups (similar to bring a cat close to
a dog).
2. Creating a suitable environment for the reaction to occur (eg
stabilizing intermediates normally very unstable).
3. Producing an alternative path for a reaction to occur.
4. Disrupting the original molecules to make them "want" to
react.
Normally a Enzyme (E) take the substrates (S) to form the products (P) as follows:
E + S ES EP E + P
1. E + S= enzyme plus substrate getting close to eachother
2. ES= enzyme-substrate complex, the species that results when the enzyme and substrate fit together in an orientation that allows a chemical reaction.
3. EP= The enzyme-product complex that results after the reaction occurs but before the two can separate (This complex is not normally shown in reactions at books but you have to know that it exist).
4. E + P= enzyme and product that have separated