Question

IN YOUR OWN WORDS, DO NOT COPY ANOTHER WEBSITE.

IN YOUR OWN WORDS: Describe exocrine secretory cells and discuss its function within the body. Talk about common locations for the type of cell and discuss the clinical significance of the cell.

Answer 1

ANS)

There are 2 main kinds of Exocrine Secretory Cells.They are:Parietal Cells and Chief Cells.

PARIETAL CELLS:

• These are the epithelial cells which release or secrete Hydrochloric acid(HCL) and the Intrinsic factor.
• Parietal cells are located in gastric glands which are seen in the border of fundus and also in the cardia of stomach.
• Parietal cells makes the stomach acid called HCL in regards to the gastrin,histamin and the acetylcholine.
• The Parietal cells have an large secretory network known as canaliculi,from there the HCL is released through active transport to the stomach.
• The parietal cells are having an pivotal role in the gastric homeostasis and also in the absorption of Cobalamin because of the secretion of the intrinsic factor.
• The Endocrine,Paracrine and Neural pathways are included in the meticulous regulation of acid discharge by the parietal cells.

CHIEF CELLS:

• Cheif cells are present in the stomach and which secretes Pepsinogen and Chymosin.
• The Pepsinogen is activated to a digestive enzyme called Pepsin at the time when that come in connection with acid made by the parietal cells.
• Pepsin is having a major role in protein digestion at the time of gastric stage of digestion.
• Chief cells are the cellular source of pepsinogen.
• Chief cell Location- Mucosal layer of stomach lining.

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