Question

In: Anatomy and Physiology

Give an accounting of how many ATP are generated through oxidative metabolism (AEROBIC GLYCOLSIS) metabolism of...

Give an accounting of how many ATP are generated through oxidative metabolism (AEROBIC GLYCOLSIS) metabolism of one molecule of glucose during exercise. Your answer should include a detailed accounting of exactly where the ATP were generated and should add up to your correct total # of ATP. Please highlight or bold your ATP counts.

Solutions

Expert Solution

ANSWER: Total ATP produced by areobic glycolysis is as follows:

Total ATP consumed during glycolysis is 2.

ATP produced at the substrate level is 2*2=4.

ATP produced at the oxidative level is 2*3=6.

Hence total ATP produced is 10.

Net ATP produced by glycolysis is 10-2=8.

ATP is consumed in the steps of conversion of glucose to glucose6phosphate and in the conversion of fructose 6 phosphate to fructose 1,6 bisphosphate.

ATP is generated in the substrate level steps - conversion of 1,3 bisphosphoglycerate to 3 phosphoglycerate and in the comversion of phosphoenolpyruvate to pyruvate.These steps takes place twice in this cycle and hence 4 ATP is generated at the substrate level.

ATP is generated in oxidative level- conversion of glyceraldehyde 3 phosphate to 1,3 bisphosphoglycerate which generates NADH+H. This step also happens twice in the cycle and 2 NADH+H is formed. This when passes through the oxidative cycle 3 ATP are formed from each molecule. Hence in total 6 ATP are formed from the Oxidative level.


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