In: Anatomy and Physiology
Give an accounting of how many ATP are generated through oxidative metabolism (AEROBIC GLYCOLSIS) metabolism of one molecule of glucose during exercise. Your answer should include a detailed accounting of exactly where the ATP were generated and should add up to your correct total # of ATP. Please highlight or bold your ATP counts.
ANSWER: Total ATP produced by areobic glycolysis is as follows:
Total ATP consumed during glycolysis is 2.
ATP produced at the substrate level is 2*2=4.
ATP produced at the oxidative level is 2*3=6.
Hence total ATP produced is 10.
Net ATP produced by glycolysis is 10-2=8.
ATP is consumed in the steps of conversion of glucose to glucose6phosphate and in the conversion of fructose 6 phosphate to fructose 1,6 bisphosphate.
ATP is generated in the substrate level steps - conversion of 1,3 bisphosphoglycerate to 3 phosphoglycerate and in the comversion of phosphoenolpyruvate to pyruvate.These steps takes place twice in this cycle and hence 4 ATP is generated at the substrate level.
ATP is generated in oxidative level- conversion of glyceraldehyde 3 phosphate to 1,3 bisphosphoglycerate which generates NADH+H. This step also happens twice in the cycle and 2 NADH+H is formed. This when passes through the oxidative cycle 3 ATP are formed from each molecule. Hence in total 6 ATP are formed from the Oxidative level.