A woman has a mutation that causes the zona pellucida to be tough and not disintegrate....

A woman has a mutation that causes the zona pellucida to be tough and not disintegrate. How would this affect her fertility? Explain.

Expert Solution

In the humans beings, after the fertilization occurs the embryo continues to develop within the zona pellucida for approximately five days. Around day 5, the normally developing embryo breaks out of the zona pellucida in a process called hatching. For this to occur successfully, the zona pellucida must thin and eventually tear to allow the embryo to emerge. Once the embryo is free of the zona pellucida, the embryo can then make direct contact with the innermost lining of the uterus - the endometrium. When this contact occurs, the embryo can implant into the uterus and the embryo can continue growing and maturing.

Women with a mutation that causes toughening of the zona pellucida after fertilization may experience infertility because early stage embryos are not able to hatch out of the zona pellucida and implant in the endometrium. In this situation, fertilization and early embryo development may occur normally, but if the embryo cannot implant then the pregnancy will not be successful.

For women undergoing infertility treatment, the challenge of tough or thick zona pellucidas can be treated using a technique called assisted hatching. While the embryo is still in vitro, embryologists use laser-assisted microscopy techniques to breach the zona pellucida. This allows the embryo to hatch shortly before implantation of the embryo into the patient's uterus.

Sydney Mullin answered 1 year ago

A mutation positioned in a nonsplicing region causes the spliceosome to recognize this mutation as being...

A mutation positioned in a nonsplicing region causes the spliceosome to recognize this mutation as being part of a consensus sequence, thereby splicing in that location. This occurred because the mutation: a. eliminated the splicing consensus sequence, causing the spliceosome to splice elsewhere b. changed the snRNA sequence, causing it to hybridize to an altered sequence on the transcript c. altered the consensus sequence in the promoter & changed the rate of transcription initiation d. created an ideal or close...

Explain the causes of Mutation. Specifically write about factors that cause Mutation

A certain genetic mutation occurs in 5% of the population of Whoville. The mutation causes otherwise...

A certain genetic mutation occurs in 5% of the population of Whoville. The mutation causes otherwise normal adult Whos to grow green tail feathers during full moons. A test for this mutation has a sensitivity of 95% and a specificity of 98%. This means that the probability that a Who with the mutation tests positive is 95%, and the probability that a Who without the mutation tests positive is 100%-98%=2%. If a random adult Who is tested for the mutation, then...

A mutation that causes cystic fibrosis has quite a high rate of people that are heterozygous...

A mutation that causes cystic fibrosis has quite a high rate of people that are heterozygous and do not show symptoms of the disease. What does this tell you about the function of the cystic fibrosis gene? a. it alters the viscosity of mucus b. the mutation is in a gene that must be 'downstream' or farther down in a metabolic pathway than others c. to have the disease phenotype, individuals only need one copy of the mutated allele d....

A loss of function mutation in Cdc25 causes cells to divide later. In yeast, this causes...

A loss of function mutation in Cdc25 causes cells to divide later. In yeast, this causes the cells to become very large over time. Specifically, explain the effect of loss of function of the Cdc-25 protein on CDK activity. Also, explain why LOF of Cdc25 would inhibit the onset of DNA replication. Rubric (4): correct interpretation of the effect on CDK-cyclin with LOF Cdc-25 (2). Correct explanation of why DNA replication would not be initiated (2).

A. A mutation in the Dorsal gene that causes the Dorsal protein to bind with high...

A. A mutation in the Dorsal gene that causes the Dorsal protein to bind with high affinity to all of the DNA binding sites for dorsal (remember normally there are low and high affinity sites in front of different genes that allow the effect of a gradient to proceed at the molecular level). 1)What will happen to the particular molecule, 2) what would happen at the cell(s) level, and 3) what would happen at the level of the whole body...

How impossible is it to actually code for a gene that causes a mutation for supernatural...

How impossible is it to actually code for a gene that causes a mutation for supernatural abilities such as flight or super strength? Not a hw question lol and probably a stupid question I'm just genuinely curious.

what type of mutation causes cancer? and how does it cause cancer?

abnormal hemoglobin that causes sickle cell is an example of a mutation that is: a)both adaptive...

abnormal hemoglobin that causes sickle cell is an example of a mutation that is: a)both adaptive in areas without malaria and maladaptive in areas with malaria b)adaptive in areas with malaria c)maladaptive in areas with malaria d)adaptive in areas without malaria

A 46-XX female fetus has a mutation that causes her to produce excess 5-alpha reductase. What...

A 46-XX female fetus has a mutation that causes her to produce excess 5-alpha reductase. What would you expect to be different at birth and why? b. How will this change at puberty and why?

Question