A mutation that causes cystic fibrosis has quite a high rate of people that are heterozygous...

A mutation that causes cystic fibrosis has quite a high rate of people that are heterozygous and do not show symptoms of the disease. What does this tell you about the function of the cystic fibrosis gene?

	a.	it alters the viscosity of mucus
	b.	the mutation is in a gene that must be 'downstream' or farther down in a metabolic pathway than others
	c.	to have the disease phenotype, individuals only need one copy of the mutated allele
	d.	the mutation probably produces a new function that was not present before
	e.	you need only one functional copy to have normal activity
	f.	the mutation is pleiotropic

Solutions

Expert Solution

gladiator answered 1 year ago

Next > < Previous

Related Solutions

What is cystic fibrosis? How does cystic fibrosis work to enhance survival for heterozygous individuals?

Cystic fibrosis is a disease in which people have a mutation in an ion channel called...

Cystic fibrosis is a disease in which people have a mutation in an ion channel called CFTR. This type of channel is found in multiple tissues throughout the body, and a simple mutation in this channel may be expressed in a multitude of ways (sweating disorder, digestive system malfunction, respiratory difficulties, etc…). This type of situation when a genetic mutation expresses itself in a multitude of phenotypes is called Select one: a. Polygenic inheritance b. Codominance c. Epistasis d. Pleiotropy...

Cystic fibrosis is caused by a mutation in a single gene. Homozygotes for this mutant recessive...

Cystic fibrosis is caused by a mutation in a single gene. Homozygotes for this mutant recessive allele (ff) have cystic fibrosis. Within a population, 2% of people have cystic fibrosis. Assuming Hardy-Weinberg equilibrium, the frequency of heterozygotes in the population is 0.24. If inbreeding was common in this population, what would happen to the percentage of people who have cystic fibrosis over time?

Cystic fibrosis is a recessive disorder. If a child comes from two heterozygous parents, what is...

Cystic fibrosis is a recessive disorder. If a child comes from two heterozygous parents, what is the chance that the child will have it too? 25% 75% 50% 100%

Cystic fibrosis (CF) is caused by a genetic mutation resulting in defective proteins in secretory cells,...

Cystic fibrosis (CF) is caused by a genetic mutation resulting in defective proteins in secretory cells, mainly in the epithelial lining of the respiratory tract. The one in every 2,000 Caucasian babies who has the disease is homozygous for the recessive mutant. Although medical treatment is becoming more effective, in the past, most children with CF died before their teens. About 20 Caucasian in 2,000 are carriers of the trait, having one mutant and one normal allele, but they do...

Cystic fibrosis (CF) is an inherited disorder that causes severe damage to the lungs, the digestive...

Cystic fibrosis (CF) is an inherited disorder that causes severe damage to the lungs, the digestive system and other organs within the body. CF affects cells that produce thin and slippery mucus and cause the secretions to become sticky and thick. CF is caused by a deletion mutation on chromosome 7. In order for a child to have cystic fibrosis they must inherit a defective gene from each of his/her parents. Rob and Jane have four children in this order:...

It has been hypothesized that people who are heterozygous for the allele that causes the deadly...

It has been hypothesized that people who are heterozygous for the allele that causes the deadly genetic condition cystic fibrosis (which, among other symptoms, reduces fertility) are more resistant to the deadly disease tuberculosis. Q9. A person who is heterozygous for the cystic fibrosis allele moves to a small, isolated community where no one previously carried the allele. If the cystic fibrosis allele protects against tuberculosis the same way the sickle-cell allele protects against malaria, what should happen to the...

It has been hypothesized that people who are heterozygous for the allele that causes the deadly...

It has been hypothesized that people who are heterozygous for the allele that causes the deadly genetic condition cystic fibrosis (which, among other symptoms, reduces fertility) are more resistant to the deadly disease tuberculosis. Suppose you travel to the future, to a time when neither cystic fibrosis nor tuberculosis have caused any deaths for many generations. In all of these future populations, the cystic fibrosis allele still exists at a low frequency. Q10. You visit a huge city with millions...

1) The DF508 allele, which causes cystic fibrosis in homozygotes, occurs at a frequency (0.02) in...

1) The DF508 allele, which causes cystic fibrosis in homozygotes, occurs at a frequency (0.02) in European populations that exceeds the background mutation rate in humans. This suggests that what process might be maintaining this relatively high allele frequency? Select one: a. Mutation b. Drift c. Selection d. None of the above 2) Which of the following could be used to differentiate two populations? Select one: a. Geography b. Allele frequencies c. Barriers to dispersal d. All of the above...

One out of 25 healthy people carries a single gene for cystic fibrosis (CF), these people...

One out of 25 healthy people carries a single gene for cystic fibrosis (CF), these people are called carriers and healthy people without a CF gene are called non-carriers. A uniformly-chosen random healthy person has probability 1/25 of being a carrier. A person with two CF genes is not healthy; they are sick (with cystic fibrosis). The child of a carrier has probability 1/2 of inheriting a CF gene from that parent. The child of two carriers inherits each of...

Subjects