Starting with the amino acids in the following peptide, Asn-Leu-Gly-Ile-Tyr-Val-Gln-Gly-Leu (Only really need this for question...

Starting with the amino acids in the following peptide, Asn-Leu-Gly-Ile-Tyr-Val-Gln-Gly-Leu (Only really need this for question two)

Describe (in words) the degradation of any one of the following (Leu, Ile, Tyr, Val) to citric acid cycle and/or ketogenic products and the degradation of two of the following (Asn, Gly, Gln) to pyruvate or citric acid cycle intermediate.
Provide details for the incorporation of any two of the amino groups from the above amino acids into urea

Expert Solution

Degradation of Tyrosine to fumarate (citric acid cycle product) and acetoacetate (ketogenic product).

Degradation of Glycine to pyruvate.

Degradation of Asparagine citric acid cycle intermediate.

Incorporation of amino groups from Leucine (Red) and Asparagine (Black) into urea.

gladiator answered 2 years ago

QUESTION 6 Which of the following peptides is most likely an alpha helix? Arg-Ala-Tyr-Pro-Met-Gly-Val-Leu-Ser-Asp Glu-Ala-Tyr-Pro-Met-Gly-Val-Leu-Ser-Lys Glu-Ala-Tyr-Phe-Met-Gln-Val-Leu-Ser-Lys...

QUESTION 6 Which of the following peptides is most likely an alpha helix? Arg-Ala-Tyr-Pro-Met-Gly-Val-Leu-Ser-Asp Glu-Ala-Tyr-Pro-Met-Gly-Val-Leu-Ser-Lys Glu-Ala-Tyr-Phe-Met-Gln-Val-Leu-Ser-Lys Arg-Ala-Tyr-Phe-Met-Gln-Val-Leu-Ser-Asp

which rptoleyic enzye would cleave this peptide into the most fragments? Asn-Met-Thr-Gln-Gly-Arg-Cys-Lys-Val-Asn-Thr-Phe-Val-His-Glu-Leu-Val-Asp-Val-Cys-Phe-Lys-Glu A. Trypsin B.Chymotrypsin C.Thermolysint...

which rptoleyic enzye would cleave this peptide into the most fragments? Asn-Met-Thr-Gln-Gly-Arg-Cys-Lys-Val-Asn-Thr-Phe-Val-His-Glu-Leu-Val-Asp-Val-Cys-Phe-Lys-Glu A. Trypsin B.Chymotrypsin C.Thermolysint D.they would all given an equal amou

The amino acid sequence of human adrenocorticotropin, a polypeptide hormone, is: Ser-Tyr-Ser-Met-Glu-His-Glu-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-Asp-Ala-Gly-Glu-Asp-Gln-Ser-Ala-Glu-Ala-Glu-Pro-Leu-Glu-Phe a)What is the appr

The amino acid sequence of human adrenocorticotropin, a polypeptide hormone, is: Ser-Tyr-Ser-Met-Glu-His-Glu-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-Asp-Ala-Gly-Glu-Asp-Gln-Ser-Ala-Glu-Ala-Glu-Pro-Leu-Glu-Phe a)What is the approximate net charge of this molecule at pH 3? ph 7? ph 9? Assume that the pKs of the terminal -NH3+ and -COOH groups are 7.8 and 3.6, respectively.

Please explain with details!!! THANK YOU! 3. Consider the following normal sequence: Gly-leu-arg-gln-cys-ile-phe And the following...

Please explain with details!!! THANK YOU! 3. Consider the following normal sequence: Gly-leu-arg-gln-cys-ile-phe And the following mutant proteins. What is the nature of each mutation? Describe what happens in each case. Gly-leu-arg-gln Gly-leu-arg-arg-cys-ile-phe Gly-phe-lys-thr-met-gln-ile Epidermolytic hyperkeratosis is an autosomal dominant condition that produces scaly skin. It can be caused by a missense mutation that substitutes a histidine (his) amino acid with an arginine (arg). Write the mRNA codons that could account for this change, and indicate if it is a...

You have purchased a protease that can specifically cleave the Gln-Gly peptide bond of the GluAsp-Asp-Tyr...

You have purchased a protease that can specifically cleave the Gln-Gly peptide bond of the GluAsp-Asp-Tyr –Asp-Gln-Gly sequence present in any protein (and it cleaves no other sequence found in proteins). Describe how you can use this protease (in combination with other purification method/s) to obtain pure protein A starting from the purified mixture of proteins A, B, and C you obtained in sub-question 2A. Assume that you will only need a very small amount of protease to cleave a...

Deduce the sequence of a heptapeptide that contains the amino acids Gly, His, Tyr, Ser, Ala, Met, and Arg, from the following experimental data

Deduce the sequence of a heptapeptide that contains the amino acids Gly, His, Tyr, Ser, Ala, Met, and Arg, from the following experimental data. Edman degradation cleaves Ala from the heptapeptide, and carboxypeptidase forms His and a hexapeptide. Treatment of the heptapeptide with chymotrypsin forms a hexapeptide and a single amino acid. Treatment of the heptapeptide with trypsin forms a pentapeptide and a dipeptide. Partial hydrolysis forms His, Ala, Tyr, and the tripeptides Ser-Gly-Met and Gly-Met-Arg. 7 amino acids total

Examine the following peptide then answer parts a-c Lys-Asp-Pro-Leu-Trp-Ala-His-Met-Gln-Phe-Gly-Arg a.estimate the net charge at pH 7...

Examine the following peptide then answer parts a-c Lys-Asp-Pro-Leu-Trp-Ala-His-Met-Gln-Phe-Gly-Arg a.estimate the net charge at pH 7 B.estimate the net charge at pH 12

Consider the following peptide: Cys-Arg-Pro-Asp-Thr-Leu-His-Lys-Gln-Glu-His How is the peptide different at pH = 6 and pH...

Consider the following peptide: Cys-Arg-Pro-Asp-Thr-Leu-His-Lys-Gln-Glu-His How is the peptide different at pH = 6 and pH 8? Which of the two pHs would you use to run an ion exchange column, and would you choose anion or cation exchange?

The ribosome catalyzes the formation of peptide bond between two amino acids. which of the following...

The ribosome catalyzes the formation of peptide bond between two amino acids. which of the following statements is true? A) the ribosomal large subunit binds to the mRNA B) The large and a small subunits of a ribosome once assembled will stay together until the degraded by the proteasome C) The catalytic site for peptide bond formation is formed primarily from an rRNA D) The number of rRNA molecules that assemble a ribosome exceeds the number of protein

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