Question

In: Anatomy and Physiology

Classify the lab tests listed by the phase of hemostasis it assesses (primary hemostasis, secondary hemostasis,...

Classify the lab tests listed by the phase of hemostasis it assesses (primary hemostasis, secondary hemostasis, fibrinolysis, inhibition):

PT, PT and INR, aPTT, bleeding time, TT, Bethesda Titer, PFA, FDP, lupus like anticoagulants, mixing studies, d-Dimers, von Willebrand factor, Fibrinogen Activity Assay, Platelet Aggregation, Factor XIII assay (Urea Solubility Test), specific factor assays, Functional Fibrinogen Assay (Clauss Method).

Solutions

Expert Solution

PRIMARY HEMOSTASIS SECONDARY HEMOSTASIS FIBRINOLYSIS INHIBITION
bleeding time PT FDP Bethesda Titer
PFA PT and INR d-Dimers lupus like anticoagulant
Platelet Aggregation aPTT
TT
mixing studies
von Willebrand factor

Fibrinogen Activity Assay

Factor XIII assay

specific factor assays

Functional Fibrinogen Assay

Primary hemostasis is a procoagulation forming process associated with initiation and formation of platelet plug.

Secondary hemostasis is a procoagulation forming process associated with propagation of clotting process via extrinsic and intrinsic coagulation cascade pathways.

Fibrinolysis is the enzymatic break down of fibrin in blood clots.

Inhibitors to coagulation factors, known as circulating anti-coagulants, are antibodies that neutralize specific clotting proteins, thereby interfering with their normal function.

PT - Prothrombin Time

INR - Interational Normalized Ratio

aPTT - activated Partial Thromboplastin Time

TT - Thrombin Time

PFA - Platelet Function Assay

FDP - Fibrin and Fibrinogen Degradation Product


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