Question

In: Anatomy and Physiology

Explain the procces of primary hemostasis?

Explain the procces of primary hemostasis?

Solutions

Expert Solution

Hemostasis is defined as arrest or stoppage of bleeding.

•STAGES OF HEMOSTASIS :-When a blood vessel is injured, the injury initiates a series of reactions, resulting in hemostasis.

It occurs in three stages -

1. Vasoconstriction

2. Platelet plug formation

3. Coagulation of blood.

Primary hemostasis involves the process till platelet plug formation. Coagulation of blood falls under secondary hemostasis.

*VASOCONSTRICTION - Immediately after injury, the blood vessel constricts and decreases the loss of blood from damaged portion. Usually, arterioles and small arteries constrict. Vasoconstriction is purely a local phenomenon. When the blood vessels are cut, the endothelium is damaged and the collagen is exposed. Platelets adhere to this collagen and get activated. The activated platelets secrete serotonin and other vasoconstrictor substances which cause constriction of the blood vessels. Adherence of platelets to the collagen is accelerated by von Willebrand factor. This factor acts as a bridge between a specific glycoprotein present on the surface of platelet and collagen fibrils.

*PLATELET PLUG FORMATION- Platelets get adhered to the collagen of ruptured blood vessel and secrete adenosine diphosphate (ADP) and throm boxane A2. These two substances attract more and more platelets and activate them. All these platelets aggregate together and form a loose temporary platelet plug or temporary hemostatic plug, which closes the ruptured vessel and prevents further blood loss. Platelet aggregation is accelerated by platelet activating factor (PAF).


Related Solutions

Classify the lab tests listed by the phase of hemostasis it assesses (primary hemostasis, secondary hemostasis,...
Classify the lab tests listed by the phase of hemostasis it assesses (primary hemostasis, secondary hemostasis, fibrinolysis, inhibition): PT, PT and INR, aPTT, bleeding time, TT, Bethesda Titer, PFA, FDP, lupus like anticoagulants, mixing studies, d-Dimers, von Willebrand factor, Fibrinogen Activity Assay, Platelet Aggregation, Factor XIII assay (Urea Solubility Test), specific factor assays, Functional Fibrinogen Assay (Clauss Method).
What laboratory tests are used to assess disorders of primary hemostasis? Secondary hemostasis?
What laboratory tests are used to assess disorders of primary hemostasis? Secondary hemostasis?
Explain the steps of hemostasis and the coagulation cascade
Explain the steps of hemostasis and the coagulation cascade
1.    Describe the following, and indicate where they are typically seen (disorders of primary hemostasis or secondary...
1.    Describe the following, and indicate where they are typically seen (disorders of primary hemostasis or secondary hemostasis) Petechiae Purpura Ecchymoses Hematomas
Describe the events that lead to hemostasis? What factors affect hemostasis
Describe the events that lead to hemostasis? What factors affect hemostasis
Describe the processes involved in hemostasis.
Describe the processes involved in hemostasis.
Which of the following statements is(are) correct? A. Hemostasis is the process by which the body...
Which of the following statements is(are) correct? A. Hemostasis is the process by which the body spontaneously stops bleeding and maintains blood in the fluid state within the vascular compartment B. Hemostasis is divided into two stages: primary and secondary C. Normal vascular endothelial cell surface is thromboresistant (or antithrombotic) D. All of the above
explain the primary advantages to investing internationally ?
explain the primary advantages to investing internationally ?
What are the primary sources of market risk and the primary sources of diversifiable risk? Explain...
What are the primary sources of market risk and the primary sources of diversifiable risk? Explain both with examples.
Arrange the following components of hemostasis in the order in which they occur, from first to...
Arrange the following components of hemostasis in the order in which they occur, from first to last.a)Platelet adhesion, b)Platelet aggregation ,c)Exposed cell wall components, d)Coagulation cascade, resulting in fibrin stabilization of platelet plug ,e)Platelet plug formation,f) Vasoconstriction , g)Vascular damage. plz put them in order a,b,c,d,e,f,g.
ADVERTISEMENT
ADVERTISEMENT
ADVERTISEMENT