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1c. Name some immune-related proteins you expect to be on the surface of RAW macrophages and...

1c. Name some immune-related proteins you expect to be on the surface of RAW macrophages and the functions of them.

1d. Regardless of the species of origin, most cell lines are derived from some kind of cancer. Why is this?

Solutions

Expert Solution

1c)  

  • immunity-related proteins are abundent on the macrophage lysosomes.
  • Mib1-it is an enzyme coded to regulate apoptosis.,
  • RhoB - is a menber of signalling rho GTP binding proteins to synthesize g proteins.
  • Gbp5 -guanylate binding protein 5 belongs to TRAFAC class dynamin like GTPase super family.it acts as an activator of NLRP3 inflammasome assembly and has a role in innate immunity and inflamation.

1 d)

  • Cancer occurs when somatic cell undergo mutation and proliferate uncontolably.
  • cell lines from these cells are developed for research to study complex biological systems as they can be grown in large numbers, and cost effective.
  • mostly these cell lines are used to study to improve the efficacy of cancer treatment.
  • cell lines are used to discover new drugs and drug testing.
  • cell lines are used invitro are important for the investigation of genetic,epi genetic cellular pathways,proliferation,deregulation,apoptosis and cancer progression.

gladiator answered 1 year ago
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