Question

In: Biology

The nucleophile that is used to free most glucose from glycogen is__________, 1. ATP 2. Tyrosine...

The nucleophile that is used to free most glucose from glycogen is__________,

1. ATP

2. Tyrosine

3. Serine

4. Inorganic phosphate

5. Water

6. Hydroxide

Solutions

Expert Solution

Answer =

The nucleophile that is used to free most glucose from glycogen is

4.Inorganic phosphate.

Explanation = The nucleophile that is used to free most glucose from glycogen is inorganic phosphate.

Glycogenolysis the process that is catabolism of glycogen into glucose.

in this process the free glucose is formed from the Glycogen.

the enzyme Glycogen phosphorylase catalyzes the releasing of glucose-1 -phosphate from the terminal alpha-1,4-glycosidic bond.

The reaction is :

(-1,4 glycogen chain)n + Pi (inorganic phosphate) (-1,4 glycogen chain)n-1  + -D glucose -1-phosphate.

most of the free glucose is present in the form of -D glucose -1-phosphate and during this process inorganic phosphate acts as a nucleophile.


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