Question

In: Biology

“Organization of Lipids in the Tear Film: A Molecular- Level View” Article. Identify a specific type...

“Organization of Lipids in the Tear Film: A Molecular- Level View” Article.

Identify a specific type of dry eye syndrome. What do the researchers believe are the causes of the condition?

Identify the main objective and aim of the researchers who wrote this article.

What is a tear film? How is it useful to the eye and what are some common ailments associated with film instabilities?

In the article, simulations were performed at different lateral compressions to reflect varying surface pressure conditions expected during an eye blink. Describe the two different behaviors the authors observed when varying the lateral compression.

What evidence allowed the authors to predict glycerine-trioleate’s (TG) position at the surface of the lipid film?

What are micelles and how they are formed?

What do the authors suggest contribute to the stabilization of the tear film during eye blinks?

Describe the results obtained from Figure 7.

Please include the APA format citation of this Peer-Reviewed article below:

Solutions

Expert Solution

Specific types of Dry eye syndromes

  • Keratitis sicca. Generally used to describe dryness and inflammation of the cornea is caused by inadequate tear film.
  • Keratoconjunctivitis sicca. Used to describe the dry eye that affects both the cornea and the conjunctiva caused by Decreased tear production or increased tear film evaporation.
  • Dysfunctional tear syndrome. Used to emphasize that inadequate quality of tears can be just as important as inadequate quantity is caused by stable and insufficient tear film.

The main objective of this study is to increase the scale of the tear-air interface and include in the study both lipids present in the tear film and those originating from the meibomian gland. And the Aim is to study biophysical properties of a realistic tear film model at the molecular level and under conditions that physiologically occur during blinking.

Micelles are spherical forms of lipids arranged themselves in liquid solutions. They formed due to their hydrophobic nature of head and hydrophilic nature of tails so that the tail is inside the spherical and head is facing towards the aqueous face.

APA format citation

Wizert, A., Iskander, DR., Cwiklik, L. (2014). Organization of Lipids in the Tear Film: A Molecular-Level View. PLoS ONE, 9(3), e92461. doi:10.1371/journal.pone. 0092461


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