Answer:
Role of cell signaling in DNA transcription and protein
synthesis:
- Cell signaling involves a complex network of
communications between cells that plays an important role in
cellular acitivities like regulation of gene expression, regulation
of metabolism,cell survival, cell differentiation etc.
DNA transcription and protein synthesis:
- Signaling molecules trigger transcription factors.
- For example NF-kB Transcription Factors are
structurally-related eukaryotic transcription factors that regulate
the expression of genes.
- NF -kB siganling pathway is involved in the transcription
regulation of cytokines, cell adhesion molecules, chemokines and
complement factors.
- Ras/MAP kinase pathway is also invovled in regulation of gene
expression
Protein Synthesis:.
- The process of protein synthesis is called as translation.
- Signaling pathways are utilized by cells to control and
regulate the process of protein synthesis.
- There are extracellular and intracellular cues to phosphorylate
proteins that play a critical role in ribosomal biogenesis and
translation initiation and elongation.
- Example of Signaling pathway that regulate eukaryotic protein
synthesis include Akt Signaling pathway.