In: Biology
5. Provide a detailed description of cell signaling through each of the following types of receptors: a. G-protein-linked receptor. b. Receptor tyrosine kinase c. Steroid hormone receptor In your discussion include all the important intermediates, conformational changes, and stages where amplification is generated.
This is really a very lengthy question . After that I will try to clear your concept as much as possible.
Signalling means conversion of extracellular signal into intracellular response.
A. GPCR:
b. Receptor tyrosine kinase :
For example epidermal growth factor (EGF) binds the EGFR to activates the tyrosine kinase activity of the EGFR receptor.
Example : RAS- MAP pathway.
c. Steroid hormone receptor: