In: Biology
Thomas hunt Morgan was a American geneticist, in 1910 he observed Drosophila melanogaster from a simple hand lens that this fly doesn't seem like other as it had white eyes, while wild type had red eyes. So he think of it that what happens to fruit flies. He work in the Morgan's Fly lab in Columbia University. So he tested by crossing this white eyed fruit fly with pure breed who have red eyes. So in F1 generation he got all red eyed fruit flies. But when he self cross them, He got 3:1 of red to white eyed fruit fly. So these results are like Mendal's experiment , so he got from it that these white eye gene are recessive. But after getting on his result he found out that white eyed fruit flies were all male. No female white eyed observed. So he hypothesis that white eyed gene might be lethal for female. But after that he crossed hetrozygous female with white eyed male fruit fly so he got result of 1:1:1:1 i.e white eyed female to red eyed female fruit fly and white eyed male to red eyed male. So he concluded from this His Chromosomal theory of inheritance. He choose fruit fly as good model organism because they are easy to breed, their life span is small. They can easily be Observed . they have similar sex chromosomes as in human, i.e XY in male and XX in female.