The entire genome of the fruit fly Drosophila melanogaster consists of 1.65 x 108 base pairs...

The entire genome of the fruit fly Drosophila melanogaster consists of 1.65 x 108 base pairs (bp). If this organism’s DNA polymerase can copy DNA at the rate of 30 bp/sec calculate the minimum time (in days) required to replicate the entire genome. Remember there are 2 strands, and each are copied at the same time. 9,900,000,000 days 4,950,000,000 days 31.83 days 1909.7 days

Expert Solution

DNA consists of two antiparallel strands. These two strands are connected by hydrogen bonds. When the replication of DNA takes place, at first two antiparallel strands are separated by the enzyme, Helicase and then DNA polymerases replicate those two strands at the same time [i.e. DNA replicates according to the Semiconservative model of replication]

Here, it is given in the question that the entire genome of the fruit fly (Drosophila melanogaster) consists of 1.65x10⁸ base pairs.

So, The one strand of this DNA consists of {(1.65x10⁸)/2} nucleotides= 8.25x10⁷ nucleotides.

Now, DNA polymerase can copy DNA at the rate of 30 bp/sec.

The time required to replicate the one strand of this DNA is={(8.25x10⁷)/30} seconds

= {(2.75x10⁶)/60} minutes

= {(4.58x10⁴)/60} hours

= (763.33)/24 days

= 31.81 days (approximately)

Two strands of DNA are copied at the same time.

Therefore, The minimum time required to replicate the entire genome is 31.81 days approximately.

So, the correct answer is 31.83 days.

gladiator answered 2 years ago

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