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In: Biology

Trying to create a question on how vitamin D is up taken in the body and...

Trying to create a question on how vitamin D is up taken in the body and the cycle that it plays a role in. I do not understand how its being uptaken within the body.

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Expert Solution

Vitamin D

  • vitamin D is a fat soluble vitamin
  • it is a sterol, it contain steroid nucleus .
  • its function like a hormone

FORM OF VITAMIN D

  • vitamin D2 (ergocalciferol)
  • vitamin D3 (cholecalciferol)

VITAMIN D UPTAKEN IN THE BODY

  • During the course of cholesterol biosynthesis 7- dehydrocholesterol is formed as an intermiate
  • on the exposure to sunlight, 7 -dehyrocholesterol is converted to cholecalciferol in the skin in dermis and epidermis.
  • dark skin pigment (melanin) adversely influence the synthesis of cholecalciferol.
  • skin is thge kargest organ in the body.
  • the production of vitamin D in the skin is directly proposional to the exposure to sunlight and inversly proportional to the pigmentation of skin
  • excessive exposure to sunlight does not result in vitamin D toxicity since excess provitamin D3 are destroyed by sunlight itself.
  • vitamin D3 maintain a calcium level in the kidney.

ROLE AND BENEFIT OF VITAMIN D

  • Vitamin D help to body absorption calcium. without enough sunshine vitamin, bone can become thin, brittle.
  • adequate vitamin D can reduce the risk of cancer
  • deficency of vitamin D which can cause alzheimer disease.
  • low levelof vitamin D which cause heart failure with high blood pressure
  • without adequate vitamin D preclampsia, gestational, diabetes, caesarean section are more common.
  • low levelof vitamin D increase the risk of inflammation and rheumatoid arthritis.
  • it can modulates cell growth.
  • immune fuction
  • gene regulation

ABSORPTION

  • vitamin D is absorbed from the small intestine for which bile is essential.

DISTRIBUTION

  • stored in adipose tissue.

METABOLISM

  • Transpotred to the liver then kidney ,where it is activated

EXCREATION

  • EXCREATED IN BILE.
  • METABOLIZED TO WATER SOLUBLE METABOLITIES AND THEN EXCREATED IN URINE AS WELL.

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