Question
In: Biology
discuss the body's acute phase response to the release of interleukin I by the monocyte/macrophage system.
discuss the body's acute phase response to the release of interleukin I by the monocyte/macrophage system.
Solutions
Expert Solution
When a pathogen invades the body, macrophages release the hormone interleukin I (IL I) and Interleukin VI (IL VI) wheich helps body to fight against pathogen. Body shows folloing responses (acute phase response) towards the release of interleukin:
1. Interleukin increses the body temperature (fever) by acting on temperature-regulating hypothalamus in the brain and by affecting energy mobilization by fat and muscle cells. This incresed temperature (fever) helps body to eleiminate infection because most of the bactria grow at normal body temperature.
2. Interleukins stimulate liver cells to release increased amount of several type of proteins in the blood stream. These proteins are known as acute phase proteins. These acute proteins bind to bacteria and activate compliment proteins which kill the bacteria.
3. In addition, interleukins also increases the number of circulating neutrophils, and eosinophils which help body to fight against infection.
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