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provide 3 reasons why it is so difficult to develop a vaccination or new antimicrobial drug...

provide 3 reasons why it is so difficult to develop a vaccination or new antimicrobial drug against malaria, even if we take anti microbial resistance out of the picture.

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Expert Solution

Answer:- Malaria is annually responsible for approximately 780000 death and more than 225 millions clinical infection worldwide. The malarial parasites have ability to make fool our immune system. There are different reasons

• Antigenic Switching (Variation) - It is a mechanism of by which some bacteria, viruses and protozoans, altering their surface antigens through genetic changes to avoid host's immune system.

• It has different forms at each development stage.

• Different location of malarial parasites in host's system that would help to hide from immune cells.

• Also Malarial Parasite express different kind of antigens.

gladiator answered 2 years ago
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