Question

• Nitroprusside: Core Drug Knowledge: indications/uses

• Sustained or Time released medications: nursing interventions •

ACE inhibitors (Captopril): Core Drug Knowledge: adverse effects

• ARB (Losartan): Core Drug Knowledge & Core Patient Variable: adverse effect, pregnancy category

• Renin Inhibitor (Aliskiren): Core Drug Knowledge: adverse effects, nursing interventions

• Dosage and Calculation: parenteral dose & IV pump calculation

Answer 1

#) Nitroprusside- Class

Antihypertensive

Vasodilator

#. Nitroprusside- Indication and uses

Hypertensive crisis

Controlled hypertension during anesthesia

Cardiac pump failure or cardiogenic shock alone or with dopamine

#. ACE inhibitor :-

Adverse Effects

-First-Dose -Hypotension

-Cough

-Hyperkalemia

-Renal Failure

-Fetal injury

-Angioedema

#. Losartan :-

Adverse effects :

CNS: Dizziness,insomnia, anxiety,confusion, abnormal dreams, migraine, tremor, vertigo, headache,malaise, depression, fatigue.

CV: Angina pectoris, 2nd Degree AV block, cerebrovascular accident, hypotension,MI, dysrhythmias.

EENT: Blurred vision, burning eyes, conjunctivitis.

GI: Diarrhea,dyspepsia, anorexia, constipation, dry mouth, flatulence, gastritis, vomiting.

GU: Impotence,nocturia,urinary frequency,UTI,, renal failure.

HEMA: Anemia, thrombocytopenia.

INTEG: Alopecia, dermatitis,dry skin, flushing,photosensitivity,rash,pruritus,sweating, angioedema.

META: Gout, hyperkalemia, hypoglycemia

MS: Cramps,myalgia, pain, stiffness.

RESP: Cough, upper respiratory infection, congestion, dyspnea, bronchitis.

#. Pregnancy category of losartan is D .

#. Aliskiren :-

Aliskiren (Tekturna) adverse effects :-

allergic reaction, angioedema, rash, hyperkalemia, and diarrhea.

#. Nursing interventions :-