Question

In: Biology

Question 9 (4 pts) The genetic term “loss of function” is used to describe any mutation...

Question 9 (4 pts)

The genetic term “loss of function” is used to describe any mutation in the DNA that leads to a particular protein that cannot function. There are many reasons why a protein may not be functioning any longer…digging into your knowledge on mechanism of gene expression and gene expression regulation, describe a mutation that could lead to a loss of function mutation. Where is the mutation in the gene? What function of gene expression or gene expression regulation is it affecting? How is it leading to a loss of function for the protein encoded for within that gene?

But I’m going to restrict your answer…describe a mechanism that DOES NOT include a point mutation leading to missense, nonsense or frameshift – in other words, choose a mutation/mechanism other than a mutation that leads to a change in the protein coding region of a mature mRNA. I want you to think outside of that particular box.


Solutions

Expert Solution

gladiator answered 1 year ago
Next > < Previous

Related Solutions

Question 9 (4 pts) The genetic term “loss of function” is used to describe any mutation...
Question 9 (4 pts) The genetic term “loss of function” is used to describe any mutation in the DNA that leads to a particular protein that cannot function. There are many reasons why a protein may not be functioning any longer…digging into your knowledge on mechanism of gene expression and gene expression regulation, describe a mutation that could lead to a loss of function mutation. Where is the mutation in the gene? What function of gene expression or gene expression...
The genetic term “loss of function” is used to describe any mutation in the DNA that...
The genetic term “loss of function” is used to describe any mutation in the DNA that leads to a particular protein that cannot function. There are many reasons why a protein may not be functioning any longer…digging into your knowledge on the mechanism of gene expression and gene expression regulation, describe a mutation that could lead to a loss of function mutation. Where is the mutation in the gene? What function of gene expression or gene expression regulation is it...
Match the term with the best definition Question 2 options: strand slippage loss of function mutation...
Match the term with the best definition Question 2 options: strand slippage loss of function mutation silent depurination in frame mutation reverse mutation Ames test suppressor expanding nucleotide repeats epigenetic pyrimidine dimers base analog Replication error nonsense mutation mutagen intercalating agent frame shift mutation base substitution 1. the alteration of a single nucleotide in DNA 2. the addition or deletion of multiples of 3 nucleotides 3. Potentially changes all amino acids downstream of mutation 4. Can change chromatin structure or...
4. [22 pts] For the function ?(?) = 2?5 − 9?4 + 12?3 − 12?2 +...
4. [22 pts] For the function ?(?) = 2?5 − 9?4 + 12?3 − 12?2 + 10? − 3 answer the following: a. [2 pts] Determine whether the function represents a polynomial. Justify your answer. b. [4 pts] Determine whether the function satisfies the Intermediate Value Theorem on the interval [0, 5]. Justify your answer. c. [2 pts] Determine the number (quantity) of complex zeros that the function has, provided the each zero is counted by its multiplicity. d. [4...
If a loss of function mutation were made in the enzyme which is reponsible for linking...
If a loss of function mutation were made in the enzyme which is reponsible for linking Okazaki fragments together, how would the results of the experiment be different? Draw a graph to show what you would expect
BIOCHEM Question An inherited mutation can lead to the loss of glucose-6-phosphatase activity. Describe how this...
BIOCHEM Question An inherited mutation can lead to the loss of glucose-6-phosphatase activity. Describe how this will affect the functioning of glycolysis and gluconeogenesis, and glycogen storage.
Gout is the result of a metabolic disorder caused by a specific genetic mutation. Describe the...
Gout is the result of a metabolic disorder caused by a specific genetic mutation. Describe the causes of gout, list three drugs used to treat it and a thorough description of their mechanism of action.
QUESTION 1 Define the term coenzyme. 2 pts. Name and describe the role of the B...
QUESTION 1 Define the term coenzyme. 2 pts. Name and describe the role of the B vitamins that function as part of the structure of coenzymes. 4 pts. QUESTION 2 Why does following a vegan diet result in risk for B-12 deficiency? 2 pts. What is Vitamin B-12 deficiency, list 3 ways to supplement for this deficiency and list when each method is appropriate. 3 pts. QUESTION 3 How do the vitamins function in the metabolic process? (list the vitamins)...
The human eye disease retinitis pigmentosa is caused by a loss of function mutation (rp) in...
The human eye disease retinitis pigmentosa is caused by a loss of function mutation (rp) in the gene PRPF31. The disease is expressed when combined with wildtype allele 1 (rp+1) in a heterozygote, but not expressed when combined with wildtype allele 2 (rp+2) in a heterozygote. When comparing the number PRPF31 mRNA transcripts in the eyes of rp/rp+1 and rp/rp+2 individuals, researchers have found a higher number of functional PRPF31 mRNAs in the eyes of rp/rp+2 individuals. This is an...
A loss of function mutation in Cdc25 causes cells to divide later. In yeast, this causes...
A loss of function mutation in Cdc25 causes cells to divide later. In yeast, this causes the cells to become very large over time. Specifically, explain the effect of loss of function of the Cdc-25 protein on CDK activity. Also, explain why LOF of Cdc25 would inhibit the onset of DNA replication. Rubric (4): correct interpretation of the effect on CDK-cyclin with LOF Cdc-25 (2). Correct explanation of why DNA replication would not be initiated (2).
ADVERTISEMENT
Subjects
ADVERTISEMENT
Latest Questions
ADVERTISEMENT