Question

Match the term with the best definition

Question 2 options:

strand slippage loss of function mutation silent depurination in frame mutation reverse mutation Ames test suppressor expanding nucleotide repeats epigenetic pyrimidine dimers base analog Replication error nonsense mutation mutagen intercalating agent frame shift mutation base substitution

1. the alteration of a single nucleotide in DNA 2. the addition or deletion of multiples of 3 nucleotides 3. Potentially changes all amino acids downstream of mutation 4. Can change chromatin structure or add amino acids 5. Changes mutant back to wild type 6. codes for a truncated polypeptide 7. mutation that often occurs in wobble position 8. Usually recessive 9. Mutation that hides the effect of another mutation, but does not reverse sequence to wild-type 10. When the wrong base is incorporated into DNA and the mismatch is not repaired and the wrong base permanently replaces the correct base 11. Insertions or deletions are incorporated into DNA by ___. 12. A spontaneous chemical change that can cause a mutation 13. Any agent that significantly increases the rate of mutation above the spontaneous rate 14. A mutagen with a structure similar to one of the four standard bases of DNA but with less stringent hydrogen bonding 15. Can induce frame shift mutations by getting in between bases 16. Mutation caused by UV radiation 17. A means of identifying mutagens 18. Changes that are heritable but not encoded by the DNA sequence and are reversible

Answer 1

Mutation are changes in DNA sequence of an organism which may or may not alter the phenotype of the organism.

If it occurs in somatic cell then it is not passed on to the next generation but is it occurs in germline cell, then it is passed on to the next generation.

The question is giving definitions of different types of mutation.

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