Question

If a loss of function mutation were made in the enzyme which is reponsible for linking Okazaki fragments together, how would the results of the experiment be different? Draw a graph to show what you would expect

Answer 1

two strands that are created when DNA is synthesized. Leading strand continually synthazised
And lagging starnd discontinuous synthazised.
l During the process of DNA replication, DNA and RNA primers are removed from the lagging strand of DNA to allow Okazaki fragments to bind to. Since this process is so common, Okazaki maturation will take place around a million times during one completion of DNA replication. For Okazaki maturation to occur, RNA primers must create segments on the fragments to be ligated. This is used as a building block for the synthesis of DNA in the lagging strand. On the template strand, polymerase will synthesize in the opposite direction from the replication fork. Once the template becomes discontinuous, it will create an Okazaki fragment.
It is then ligated by liage to form complete strand.defect ligase cause
d efects in the maturation of Okazaki fragments can potentially cause strands in the DNA to break and cause different forms of chromosome abnormality. These mutations in the chromosomes can affect the appearance, the number of sets, or the number of individual chromosomes.