Question

In: Anatomy and Physiology

1. Drug effects at receptors are a combined results of the drugs affinity for the receptor...

1. Drug effects at receptors are a combined results of the drugs affinity for the receptor and an inherent property of the drug known as its:
A) potency
B) cooperativity
C) intrinsic activity

2. The term xenobiotic refers to
A) drug metabolism by bacteria
B) metabolism by non-human organisms
C) a foreign molecule not normally found in the body. It may or may not be a drug.

Solutions

Expert Solution

1. Drug effects at receptors are a combined results of the drugs affinity for the receptor and an inherent property of the drug known as its:

Answer: (C) Intrinsic activity.

Traditional receptor theory frames that a drug can be characterized as agonist or antagonist which is solely based on the inherent property of the drug known as intrinsic efficacy.

Affinity is the ability to bind to the target receptor and intrinsic efficacy is the ability to  change receptor activity to produce a response.

  • Agonists are drugs with both affinity and intrinsic efficacy.
  • Antagonists have affinity but zero intrinsic efficacy which do not produce a response upon binding.

2. The term xenobiotic refers to

Answer:(C) a foreign molecule not normally found in the body. It may or may not be a drug.

Presence of achemical substance within an organism is called as xenobiotic. They are not naturally produced within the organism. Examples of xenobiotics are: drugs, food additives, and environmental pollutants


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