In: Anatomy and Physiology
Drugs may cause side effects because:
Select one:
A. the receptors may be found in more than one location in the body.
B. the target is an enzyme, and all enzyme targets cause side effects.
C. the drug has been poorly manufactured.
D. Any of the above are possible explanations.
Answers :
D. Any of the above are possible explanation.
Physiologic functions (e.g, contraction, secretion) are usually regulated by multiple receptor mediated mechanisms, and several steps (e.g,receptor coupling, multiple intracellular 2nd messenger substances) may be interposed between the initial molecular drug-receptor interaction and ultimate tissue or organ response. Thus, several dissimilar drug molecules can often be used to prouce the same desired response.
Drug target as a nucleic acid or a protein (e.g. an enzyme, a receptor) whose activity can be modified by a drug. The drug can be a small molecular weight chemical compound or a biological, such as an antibody or a recombinant protein. The drug target should have been shown to be effective/ mechanistically involved in the disease by relevant in vitro or vivo models.
Poor quality medicines presents a serious health problem. Some drugs can't help but trigger side effects because if their chemical structure and poorly manufacture drug, it is blocks the drug receptors and cause side effects.