In: Nursing
Drug Cards for the following medications that describe the Drug class, Prototype Name, MOA, Major Adverse Effects, Drug Interactions and Contraindications, and Nursing Implications
Estrogen
Tamoxifen
Oral Contraceptives as a group
Clomiphene
Medication is chemical compound which is prescribed to treat condition. medication can be given to patients according to the prescription. while givng medication, the nurse has to follow 5 rights
the following medication are estrogen, oral contraceptives, tamoxifen, clomiphene
name | Drug Class | prototype name | Mode of action | major adverse effcets | drug interactions | contraindicactions | nursing implications |
Estrogen | Hormone | estradiol | it binds with intracellular that stimulate DNA and RNA to produce produce proteins for the acion of estrogen.it increases growth and developments of female sex organs and secondary sex characterstics and it is used in defiicency conditions | it causes edema, hypertension,headache, gynecomastia, hyperglycemia, increase eight, depression, differences in menstraual bleeding and electrolyte changes | dosage of hypoglycemic and anticogulants should be changed. its effectiveness decreases with rifampin and barbiturates | pregnancy and lactation, thromboembolic disease, vaginal bleeding |
it should be administered after food to reduce nausea and advise to take solid food explains signs and symptoms of fluid accumulation advice to apply sun screen lotion and protective dress to pretect from darkness instruct the use of applicator |
Tamoxifen | antineoplastic |
estrogen receptor antagonist tamoxifen |
it competes with estrogen for binding sites in breast and other tissues and decreases DNA synthesis and estrogen reacts |
vaginal bleeding , nausea, depression, headache, thrombocytopenia, hypercalcemia photosensitivity |
estrogen reduce the action of tamoxifen | hypersensitivity, prgenancy, lactation |
it should be administered with food o avoid irritation advice to check daily educate about tumor illinitially increase insize temporarily educate to take analgesic if she has bone pain |
OralContraceptives | hormones | estradiol and norgestrel | it prevent follicle development, ovulation, corpus luteum |
hypertension, breast tenderness, abdominal bloating,nausea, stomach upset, spotting, dizziness, photosensitivity |
antibiotic mainly rifampin, anticonvulsants reduce effect of oral contraceptive pills | undiagnosed genital bleeding, coronary artery disease, thromboembolic disease and thrombophlebities, pregnancy,liver tumor, diabetes with vascular complications, cerebrovascular disease |
assess blood pressure advise to eat solid food to decrease nausea explain sign and symptoms of fluid accumulation instruct to apply sunscreen and dress to avoid photosensitivity |
Clomiphene | Hormone | clomiphene citrate |
oral nonsteriodal estrogen agonist it stimulates release of pituitary gonadotrophins , FHSand LH that causes ovulation and development of corpus luteum |
flushing, ovarian enlargemnet, breast discomfort, nervouseness, restlessness,breast discomfort, nausea, vomiting, distension increased urine frequency and its volume | there isno drug interactions |
it is contraindicated in liver disease, pregnanacy, ovarian cysts, poly cystic ovarian syndrome |
advice to take medication as advised instruct to have conceive with sexual contact every other day starting 48 hr before ovulation educate about measuring basal body temperture advice to withdraw medication if conception is suspected |