Question

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1. A physician orders 2000 units of heparin to be administered by intravenous infusion per hour. The...

1. A physician orders 2000 units of heparin to be administered by intravenous infusion per hour. The pharmacy provides a heparin IV bag containing 25,000 units of heparin in 250 ml of D5W. How many ml should be administered per minutes?

2.A male patient weighing 85 kg is placed on heparin therapy for the prevention of deep vein thrombosis after surgery. How many ml of a heparin injection containing 5000 units/ml should be administered for a loading dose of 75 units/kg?

3. Following the question 2, what should be the infusion rate in ml/hr, using a solution that contains heparin 25000 units/500 ml, to administer 18 units/kg/hr?

Expert Solution

1. Available dosage: 25000 units/250 ml = 100 units / ml

Ordered dosage: 2000 units/hour

Formula: ordered dosage / available dosage

= 2000 / 100 = 20 ml / hour

Answer: ml/ min= 20ml / 60mins = 0.33 ml/min

2. Available dosage: 5000 units / ml

Weight: 85 kg

Ordered dosage: 75 units / kg = 75*85= 6375 units

Formula: ordered dosage/ available dosage

Answer = 6375 / 5000 = 1.275 ml

3. Available dosage: 25000 units / 500 ml = 50 units / ml

Weight: 85 kg

Ordered dosage: 18 units/kg/hr=18*85=1530 units/hr

Formula: ordered dosage / available dosage

Answer: 1530 / 50 = 30.6 ml / hour

Nightingale answered 2 years ago

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