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a sterile ophthalmic preparation contains 0.6% besifloxacin (E= 0.08) in 5 ml container. calculate the quantity...

a sterile ophthalmic preparation contains 0.6% besifloxacin (E= 0.08) in 5 ml container. calculate the quantity of sodium chloride required for isotonicity

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Expert Solution

sterile ophthalmic preparation contains 0.6% besifloxacin in 5 ml container.

0.6% of besifloxacin means(The weight of besifloxacin in the solution)

0.6gm/100ml * 5ml = 0.03gm of besifloxacin present in 5 ml container.

E value is 0.08

So,

0.08 * 0.03 =0.0024 GM

Ans. 0.0024 gm of sodium chloride required for isotonicity.


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