Question

22.Enzymes of blood plasma and their role in enzymodiagnostics.(biochemistry)

(please explain with more explanation its my final exam question...thank you ! :))

Answer 1

22) There are a number of enzymes in in bloodplasma like ATPases, anion transport protein, glyceraldehyde 3-phosphate dehydrogenase, protein kinases, adenylate cyclases, acetylcholinesterase.

ATPase is used to transport a variety of compounds like ions and phospholipids, across a membrane using ATP hydrolysis of energy.

Band 3 anion transport protein is a phylogenetically preserved transport protein responsible for mediating the exchange of chloride (cl-) with the bicarbonate (HCO3-) across plasma membranes. Different other members like AE2 and AE3 also have the simmilar function of the AE clade.

Glyceraldehyde 3 phosphate dehydrogenase is an enzyme that helps in catalysing the sixth step of glycolysis and thus serves to break down glucose for energy and carbon molecules.

Protein kinases are enzymes that regulate the biological activity of proteins by phosphorylation of specific amino acids with ATP as the source of phosphate ,thereby introducing a confirmational change from an inactive to an active form of the protein.

Adenylate cyclases is the most widely distributed effector protein and is responsible for converting ATP to the second messenger cAMP.

Acetylcholinesterase is considered as a key enzyme in biological nerve condition . In the cholinergic synapse, the enzyme degrades acetylcholine ,stoppping the neurotransmitter's excitwtory effects on the post synaptic membrane and ensures the normal delivery of nerve signals in the organisms.

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