QUESTION: What class of antibiotics may cause
tendon rupture?
ANSWER:
- The class of antibiotic known as
Fluoroquinolones may cause tendon rupture.
- It increases the chances that a patient can injure their
Achilles tendon.
QUESTION: What makes it more likely to
occurs?
ANSWER:
- Generally fluoroquinolones class of antibiotics most commonly
involves in weight bearing tendons.
- Mostly fluoroquinolones have been formulate to compromises the
function of tendon which increase the risk of injury.
- This class of antibiotic cause the tissue injury directly.
- By stimulating local release of tissue damaging substances, it
also indirectly generate toxicity which includes oxygen derived
species and nitric oxide.
- Fluoroquinolones also known as chelators of cations which
deplete divalent ion necessary for suitable integrin receptor
signaling.
QUESTION: What instructions should be given to
the patients when prescribing this class of antibiotics?
ANSWER:
Instructions:
- Take the medicine with a full glass of water.
- Even if you feel better you should be keep taking your medicine
until it finished.
- If you take ofloxacin and norfloxacine, then you have to take
fluoroquionlones class of antibiotics in empty stomach that means
two hours after eating or thirty miniutes before eating.
- If you take two doses, then you have to take it alternatively
in day and night.
- If you skip to take the dose then do not take it overdose to
complete.