Question

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Type 4 hypersensitivity reactions are responsible for which of the following? contact sensitivity elimination of tumor...

Type 4 hypersensitivity reactions are responsible for which of the following?

  • contact sensitivity

  • elimination of tumor cells

  • serum sickness

  • rejection of foreign tissue graft

Solutions

Expert Solution

Hypersensitivity is of 4 types :- type 1, type 2, type 3 and type 4.

Type 4 Hypersensitivity is mediated by CD4+T Cells and CD8+ T Cells.

CD4+ T Cell mediated Hypersensitivity is in autoimmunity. ( Contact sensitivity ).

CD8+T Cell mediated Hypersensitivity acts against viral infection , tumor cells and graft rejection.

Therefore, contact sensitivity , elimination of tumor cells, rejection of foreign tissue graft is by type 4 Hypersensitivity.

Serum sickness is by type 3 Hypersensitivity.


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